Many severe symptoms in Parkinson’s disease are caused by the degeneration of the brain’s dopamine neurons. Transplantation of stem cell-derived dopamine neurons to patients with Parkinson’s disease is a therapeutic approach that is getting close to...
Read More »RNA Sequencing Library FAQs
Here, we answer some FAQs about RNA-seq and RNA sequencing libraries. What is RNA sequencing? RNA sequencing (RNA-seq) is a tool used to study the transcriptome – the total RNA molecules present in one or a collection of cells, including protein coding RNAs ...
Read More »Identifying cell types from single-cell RNA sequencing data
Identifying different types of cells within a tissue or an organ can be very challenging and time-consuming. Methods to identify cell types from single-cell RNA sequencing data have been...
Read More »Quantitative miRNA profiling: how to choose the best RNA sequencing method?
RNA sequencing (RNA-seq) is a widely used method employing next generation sequencing (NGS) to discover and quantify the abundance of RNA...
Read More »Targeted single-cell RNA sequencing maximizes cellular information at a lower cost
Single-cell RNA-sequencing (scRNA-seq), which quantifies individual cells’ mRNA expression of an unbiased set of genes, has become an important tool for assessing heterogeneity within cellular populations...
Read More »RNA Sequencing study identifies group of genes with altered expression in autism
Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another...
Read More »NVIDIA Expands NVIDIA Clara, introduces GPU-accelerated RNA-sequencing pipelines to fight COVID-19
In a major expansion of the NVIDIA Clara™ healthcare platform, NVIDIA today announced breakthrough performance, key partnerships and new capabilities to help the medical...
Read More »New sequencing technology will show how lncRNA regulates gene activity
The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects. An international team including a bioinformatician from the Research Center...
Read More »Direct capture Perturb-seq – CRISPR meets single-cell RNA sequencing to offer unprecedented detail and depth of insight from such genetic disruption studies
By disrupting the expression of a particular gene and observing how this change affects expression of other genes, researchers can learn about the cellular roles of the disrupted gene. New technologies such as Perturb-seq offer unprecedented detail and depth of...
Read More »Revealing the Transcriptome with RNA-Seq
Ribonucleic acid—RNA—gives scientists a way to analyze gene expression. Getting the best results, though, depends on analyzing the right RNA in an effective way. Increasingly, scientists select RNA...
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