Single-cell RNA-sequencing (scRNA-seq) is becoming indispensable in the study of cell-specific transcriptomes. However, in scRNA-seq techniques, only a small fraction of the genes are captured due to “dropout” events. These dropout events require...
Read More »News
RNA sequencing as an alternative tool for detecting measurable residual disease in fusion gene-driven subtypes of AML
DNA sequencing-based measurable residual disease (MRD) detection has shown to be clinically relevant in AML. However, the same methodology cannot be applied to fusion gene-driven subtypes of AML such...
Read More »Featured RNA-Seq Job – Bioinformatics/Technical Support – NGS
Data analysis and post delivery technical support for genomics products/services with a focus on NGS. Bioinformatics Generate NGS data reports – from raw data to analysis report following established data analysis pipelines. (e.g. mapping, de novo assembly, expression analysis, variant ...
Read More »Postdoc position available
Postdoctoral Fellowship in Bioinformatics/ Integrative Genomics of Chronic Lung Diseases Brigham and Women’s Hospital and Harvard Medical School The Channing Division of Network Medicine at Brigham and Women’s Hospital is looking for an exceptional postdoctoral fellowship candidate to join the ...
Read More »Triple RNA-Seq reveals synergy in a human virus-fungus co-infection model
Infections with two pathogens pose a serious threat in the clinics. Researchers from Würzburg and Jena have developed a technique that provides new...
Read More »Measuring intracellular abundance of lncRNAs and mRNAs with RNA sequencing and spike-in RNAs
Long noncoding RNAs (lncRNAs) play essential roles in normal physiology and in disease but their mechanisms of action can be challenging to identify.
Read More »DBiT-seq – deterministic barcoding in tissue enables NGS-based spatial multi-omics mapping
Because of the very complicated organization of tissues and cells, it’s still not entirely understood how tumors form, for instance, or how different...
Read More »Researchers find that a type of RNA monitors the genome to help ensure its integrity
Deep inside your cells, DNA provides the instructions to produce proteins, the essential molecules that grow and maintain your body. RNA is the...
Read More »[Dolomite Bio Webinar] Single Cell Research Without Constraints
In recent years, new single cell technologies have revolutionized our understanding of cell identity and diversity and enabled research to be carried out at an unprecedented resolution. The shift from bulk to single cell methods...
Read More »Prediction of single-cell gene expression for transcription factor analysis
Single-cell RNA sequencing is a powerful technology to discover new cell types and study biological processes in complex biological samples. A current...
Read More »