In the past 5 years, RNA-Seq approaches, based on high-throughput sequencing technologies, are becoming an essential tool in transcriptomics studies. It is now commonly accepted that a normalization preprocessing step can significantly improve the quality of the analysis, in particular, ...
Read More »New method of measuring absolute RNA copy numbers redefines our ability to perform quantitative biology
Transcript regulation is essential for cell function, and misregulation can lead to disease. Despite technologies to survey the transcriptome, we lack a comprehensive understanding of transcript kinetics, which limits quantitative biology. This is an acute challenge in embryonic development, where ...
Read More »