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Tag Archives: CEA

Detection of generic differential RNA processing events from RNA-seq data

February 9, 2016 Leave a comment 3,987 Views

rna-seq

RNA-seq data analysis has revealed abundant alternative splicing in eukaryotic mRNAs. However, splicing is only one of many processing events that transcripts may undergo during their lifetime. Researchers from the Institute for Integrative Biology of the Cell, CNRS present here ...

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Recent RNA-SEQ Pubs

Prepubertal exposure to a high dose of cadmium induces hypothalamic injury through transcriptome profiling alteration and neuronal degeneration in female rats.
Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates.
Aethionema arabicum genome annotation using PacBio full-length transcripts provides a valuable resource for seed dormancy and Brassicaceae evolution research.
Genome-Wide Discovery of Natural Variation in Pre-mRNA Splicing and Prioritizing Causal Alternative Splicing to Salt Stress Response in Rice.
NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway.
HAND1 and BARX1 act as transcriptional and anatomic determinants of malignancy in gastrointestinal stromal tumor.

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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    Associate Professor

    7 hours ago
  • rna-seq

    Using single-cell RNA sequencing to disentangle the blood system

    3 days ago
  • rna-seq

    Arriba – accurate and efficient detection of gene fusions from RNA sequencing data

    3 days ago
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    MSRG – new database of mosquito small RNA transcriptomes

    4 days ago
  • rna-seq

    Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in the lungs

    4 days ago
  • rna-seq

    Genuity Science wins 2021 BIG Innovation Award for novel approach to analysis of single-cell RNA sequencing data

    4 days ago
  • rna-seq

    CLInt-Seq – a method to more efficiently isolate and identify rare T cells

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