Tag Archives: chip-seq

While there are sophisticated resources available for displaying NGS data, including the Integrative Genomics Viewer (IGV) and the UCSC genome browser, exporting regions and assembling figures for publication remains challenging. In particular, customizing track appearance and overlaying track replicates is ...

With the help of high-throughput NGS (next-generation sequencing) technologies, ancestral transcriptome reconstruction is helpful to understand the complexity of transcriptional regulatory systems that underlies the evolution of multiple cellular metazoans with sophisticated functions and distinctive.,,

ChIP-Seq / ATAC-Seq Analysis and Integration with Gene Expression Data ChIP-Seq and ATAC-Seq empower researchers to learn how gene expression is regulated by transcription factors, histone modifications, and chromatin accessibility. But processing and analyzing the data can be difficult. In ...

Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methylation (DNAme) and specific histone...

Version3.0 is now available for download !! Download CSBB-v3.0 from GitHub or Source Forge : GitHub : https://github.com/csbbcompbio/CSBB-v3.0 Source Forge: https://sourceforge.net/projects/csbb-v3-0/?source=navbar Major Highlights of version 3.0: *RNA-Seq processing for human, mouse, frog and zebrafish *ChIP-Seq processing for human, mouse and frog *ATAC-Seq ...

One commonly performed bioinformatics task is to infer functional regulation of transcription factors by observing differential expression under a knockout, and integrating DNA binding information of that...

A Computational Biologist or Bioinformatician position is offered by the laboratory of Dr. Maite Huarte of CIMA research institute in Pamplona, Spain. The position is funded by the European Research Council (ERC) with the possibility of at least a 5-year ...

Heatmaps are an indispensible visualization tool for examining large-scale snapshots of genomic activity across various types of next-generation sequencing datasets. However, traditional heatmap software do not typically offer multi-scale insight across multiple layers of genomic analysis (e.g., differential expression analysis, ...

Next-generation sequencing (NGS) has revolutionized how research is carried out in many areas of biology and medicine. However, the analysis of NGS data remains a major obstacle to the efficient utilization of the technology, as it requires complex multi-step processing ...

Data integration has become a useful strategy for uncovering new insights into complex biological networks. Researchers at the German Rheumatism Research Center studied whether this approach can help to delineate the signal transducer and activator of transcription 6 (STAT6)-mediated transcriptional ...