Tag Archives: circRNAs

CIRI – de novo circular RNA identification

rna-seq

Recent studies reveal that circular RNAs (circRNAs) are a novel class of abundant, stable and ubiquitous noncoding RNA molecules in animals. A comprehensive detection of circRNAs from high-throughput transcriptome data is an initial and crucial step to study their biogenesis ...

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Cofactor Genomics Awarded NIH Grant to Develop a Circular RNA Enrichment Kit and Reference Profile

rna-seq

August 2014, Cofactor Genomics has been awarded a grant by the National Institute of Mental Health (NIMH), an institute of the NIH, to develop a standardized enrichment kit and define the normal reference profile for circular RNAs (circRNA) in the nervous ...

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Detecting and characterizing circular RNAs

rna-seq

Circular RNA transcripts were first identified in the early 1990s but knowledge of these species has remained limited, as their study through traditional methods of RNA analysis has been difficult. Now, novel bioinformatic approaches coupled with biochemical enrichment strategies and ...

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