Researchers combine CRISPR gene editing and single cell genomic profiling

December 19, 2016 Leave a comment 7,330 Views

A new combined method may finally give scientists a tool fine enough to probe life’s most nuanced processes What combinations of mutations help cancer cells survive? Which cells in the brain are involved in the onset of Alzheimer’s? How do ...

Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation

August 22, 2016 Leave a comment 5,369 Views

Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification. However, it is not fully understood how individual stem cells exit the pluripotent state and transition towards their ...

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Tag Archives: CRISPR/Cas9

Researchers combine CRISPR gene editing and single cell genomic profiling

Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation

EMBR-seq – Enrichment of mRNA by blocked rRNA for bacterial RNA sequencing

rssNMF – A robust semi-supervised NMF model for single cell RNA-seq data

Benchmarking algorithms for pathway activity transformation of single-cell RNA-seq data

scRNA-Seq reveals there are two types of thirst

DBiT-seq – in-tissue barcoding for spatially revolved whole transcriptome sequencing at cellular level

Tempora – Cell trajectory inference using time-series single-cell RNA sequencing data

Upcoming webinar – Cluster Ensemble and Batch Correction Methods for Single Cell RNA-Sequencing Data