Researchers combine CRISPR gene editing and single cell genomic profiling

December 19, 2016 Leave a comment 7,644 Views

A new combined method may finally give scientists a tool fine enough to probe life’s most nuanced processes What combinations of mutations help cancer cells survive? Which cells in the brain are involved in the onset of Alzheimer’s? How do ...

Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation

August 22, 2016 Leave a comment 5,456 Views

Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification. However, it is not fully understood how individual stem cells exit the pluripotent state and transition towards their ...

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Tag Archives: CRISPR/Cas9

Researchers combine CRISPR gene editing and single cell genomic profiling

Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation

Using single-cell RNA sequencing to disentangle the blood system

Arriba – accurate and efficient detection of gene fusions from RNA sequencing data

MSRG – new database of mosquito small RNA transcriptomes

Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in the lungs

Genuity Science wins 2021 BIG Innovation Award for novel approach to analysis of single-cell RNA sequencing data

CLInt-Seq – a method to more efficiently isolate and identify rare T cells

Response to infection therapy better understood thanks to a new sequencing technique