ATDBio, a leader in complex oligonucleotide synthesis, and a research team at the Botnar Research Centre, University of Oxford, have been awarded funding by Innovate UK, the UK’s Innovation Agency, to improve single-cell RNA sequencing...
Read More »A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies
The recently developed droplet-based single-cell transcriptome sequencing (scRNA-seq) technology makes it feasible to perform a population-scale scRNA-seq study, in which the transcriptome is measured...
Read More »dropEst – pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing...
Read More »Dolomite Bio introduces the Nadia product family for single cell research
Dolomite Bio is delighted to announce the launch of the game-changing Nadia single cell platform, a groundbreaking system set to escalate scRNA-Seq to new heights, offering the fast-growing single cell research sector an innovative solution for a wide range of ...
Read More »DroNc-Seq – Single-nucleus RNA sequencing, droplet by droplet
DroNc-Seq — a technology that merges single-nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues. from The Broad Institute by Tom Ulrich – Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This ...
Read More »Correcting droplet-based single-cell RNA-seq experiments
Single-cell RNA-seq protocols provide powerful means for examining the gamut of cell types and transcriptional states that comprise complex biological tissues. Recently-developed approaches based on droplet microfluidics, such as inDrop or Drop-seq, use massively multiplexed barcoding to enable simultaneous measurements ...
Read More »A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas
Although the function of the mammalian pancreas hinges on complex interactions of distinct cell types, gene expression profiles have primarily been described with bulk mixtures. Here researchers from the Israel Institute of Technology implemented a droplet-based, single-cell RNA-seq method to ...
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