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Tag Archives: fluorosis

RNA-Seq reveals how too much fluoride causes defects in tooth enamel

February 20, 2020 Leave a comment 943 Views

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Changes Within Enamel Cells Point to Mechanism by Which Excessive Fluoride Leads to FluorosisExposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel—a novel explanation for...

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Recent RNA-SEQ Pubs

Cardioprotection of Panax Notoginseng saponins against acute myocardial infarction and heart failure through inducing autophagy.
METTL3 restrains papillary thyroid cancer progression via m6A/c-Rel/IL-8 mediated neutrophils infiltration.
Identify immune-related genes of adzuki bean weevil (Callosobruchus chinensis) in response to bacteria challenge by transcriptome analysis.
Galectin-1-RNA interaction map reveals potential regulatory roles in angiogenesis.
Coconut genome assembly enables evolutionary analysis of palms and highlights signaling pathways involved in salt tolerance.
RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization.

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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  • The BD AbSeq workflow integrated into the BD Rhapsody system

    Single-cell Multi-Omics: Marrying RNA Seq to protein expression and more

    3 days ago
  • rna-seq

    NASA GeneLab RNA-Seq Consensus Pipeline – Standardized Processing of Short-Read RNA-Seq Data

    3 days ago
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    New approach emerges to better classify, treat brain tumors

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    The biotech company baseclick GmbH launched a new and highly efficient method for SARS-CoV-2 mutation analysis

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