Tag Archives: Immunoprecipitation

Identifying microRNA targets using AGO-RIPseq

rna-seq

microRNAs (miRNA) are small, noncoding RNAs that bind to messenger RNAs (mRNAs) and regulate their activity. They are, therefore, important posttranscriptional regulators. In recent years it has become clear that miRNAs regulate large genetic networks, rather than single genes, and ...

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Identifying RBP Targets with RIP-seq

rna-seq

One of the challenges to assess the impact of RBPs on posttranscriptional gene regulation is identifying and quantifying the RNA and protein components of ribonucleoprotein complexes (RNPs) in a cellular context. The human genome is estimated to contain 1542 RBPs. ...

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