A subset of cancer-associated fibroblasts (FAP+/CAF-S1) mediates immunosuppression in breast cancers, but its heterogeneity and its impact on immunotherapy response remain unknown...
Read More »quanTIseq – estimate the fractions of ten different immune cell types from RNA-Seq data
Researchers from Medical University of Innsbruck introduce quanTIseq, a method to quantify the fractions of ten immune cell types from bulk RNA-sequencing data. quanTIseq was extensively validated in blood and tumor samples using simulated, flow...
Read More »Upcoming Webinar – Applications of TCR repertoire as a biomarker for immunotherapy and beyond
Date: Thursday, May 23, 2019Time: 10AM PDT | 1PM EDTSpeaker: Dr. Ankita DasCheckpoint inhibitors have produced durable responses, even cure, in patients who have failed all therapies. This phenomenon is unprecedented in cancer treatment...
Read More »Imaging biopsies as effective as RNA-Seq?
A computational imaging-based signature of immune-cell infiltration in and around a tumor could predict patients’ responses to treatment with anti-PD1/PDL1 immunotherapies, according to data from a study presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held ...
Read More »Featured Job Opening – Software Development Manager
Firma – OncoImmunity AS Sted – Oslo Cancer Cluster Incubator, Ullernchausséen 64, Oslo 0379 Oslo Frist – 31.01.2016 Varighet – Fast Sektor – Privat Stillingstittel – Software development manager Bransje – Helse og omsorg / IT – programvare Stillingsfunksjon IT ...
Read More »An immunotherapy gene signature in several cancer types that is not detected by traditional differential expression analyses
The tumour microenvironment is the non-cancerous cells present in and around a tumour, including mainly immune cells, but also fibroblasts and cells that comprise supporting blood vessels. These non-cancerous components of the tumour may play an important role in cancer ...
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