Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-Seq data

July 24, 2015 Leave a comment 3,814 Views

Understanding the regulation of gene expression, including transcription start site usage, alternative splicing, and polyadenylation, requires accurate quantification of expression levels down to the level of individual transcript isoforms. To comparatively evaluate the accuracy of the many methods that have ...

Astroid – transcriptome reconstruction on the basis of a flow network

September 30, 2014 Comments Off on Astroid – transcriptome reconstruction on the basis of a flow network 4,100 Views

The advancement of RNA sequencing (RNA-seq) has provided an unprecedented opportunity to assess both the diversity and quantity of transcript isoforms in an mRNA transcriptome. In this paper, researchers from the University of Kentucky revisit the computational problem of transcript ...

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Tag Archives: isoform abundance

Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-Seq data

Astroid – transcriptome reconstruction on the basis of a flow network

EMBR-seq – Enrichment of mRNA by blocked rRNA for bacterial RNA sequencing

rssNMF – A robust semi-supervised NMF model for single cell RNA-seq data

Benchmarking algorithms for pathway activity transformation of single-cell RNA-seq data

scRNA-Seq reveals there are two types of thirst

DBiT-seq – in-tissue barcoding for spatially revolved whole transcriptome sequencing at cellular level

Tempora – Cell trajectory inference using time-series single-cell RNA sequencing data

Upcoming webinar – Cluster Ensemble and Batch Correction Methods for Single Cell RNA-Sequencing Data