Isoform-level gene expression patterns in single-cell RNA-sequencing data

January 21, 2016 Leave a comment 4,330 Views

RNA-sequencing of single-cells enables characterization of transcriptional heterogeneity in seemingly homogenous cell populations. In this study, reseachers from the Karolinska Institute propose and apply a novel method, ISOform-Patterns (ISOP), based on mixture modeling, to characterize the expression patterns of pairs ...

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