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Tag Archives: La Jolla Institute for Immunology

RNA-seq reveals why every COVID-19 case is different

October 8, 2020 Leave a comment 1,531 Views

rna-seq

As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others. To solve this puzzle, scientists need an in-depth understanding of how the ...

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Recent RNA-SEQ Pubs

Differential gene expression patterns in spermatozoa from teratospermic and normospermic domestic cats.
The Bromodomain Containing 8 (BRD8) Transcriptional Network in Human Lung Epithelial Cells.
The study of single cells in diabetic kidney disease.
SUSCC: Secondary Construction of Feature Space based on UMAP for Rapid and Accurate Clustering Large-scale Single Cell RNA-seq Data.
Comprehensive Analysis of Transcript and Protein Relative Abundance During Blood Stages of Plasmodium falciparum Infection.
De novo genome assembly of two tomato ancestors, solanum pimpinellifolium and S. lycopersicum var. cerasiforme, by long-read sequencing.

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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Recent News

  • The BD AbSeq workflow integrated into the BD Rhapsody system

    Single-cell Multi-Omics: Marrying RNA Seq to protein expression and more

    1 day ago
  • rna-seq

    NASA GeneLab RNA-Seq Consensus Pipeline – Standardized Processing of Short-Read RNA-Seq Data

    1 day ago
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    New approach emerges to better classify, treat brain tumors

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    5th RNA Symposium – “Processing RNA”

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  • baseclick

    The biotech company baseclick GmbH launched a new and highly efficient method for SARS-CoV-2 mutation analysis

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    RNA sequencing of wastewater useful for control of SARS-CoV-2

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