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Conventional two-dimensional differentiation from pluripotency fails to recapitulate cell interactions occurring during organogenesis. Three-dimensional organoids generate complex organ-like tissues; however, it is unclear how heterotypic interactions affect lineage identity. Here researchers from the Max Planck Institute for Evolutionary Anthropology use ...
Read More »RNA-Seq reveals the multilineage communication that regulates human liver bud development from pluripotency
