Cellular lineage trees can be derived from single-cell RNA sequencing snapshots of differentiating cells. Currently, only datasets with simple topologies are available. To test and further develop tools for lineage tree reconstruction, we need test datasets with known complex topologies. ...
Read More »High-throughput single-cell RNA sequencing and data analysis
Understanding biological systems at a single cell resolution may reveal several novel insights which remain masked by the conventional population-based techniques providing an average readout of the behavior of cells. Single-cell transcriptome sequencing holds the potential to identify novel cell ...
Read More »Single-cell RNA-Seq analysis aids researchers in the bioengineering of 3D liver tissues
Scientists discover that three-dimensional liver buds grown in a dish from stem cells mimic the molecular signatures observed during the natural development of human liver An international team of researchers led by Barbara Treutlein of the Max Planck Institute for ...
Read More »Featured Job – Technical Assistant (m/f) (RNA-seq experience)
Max Planck Institute for Infection Biology http://www.mpiib-berlin.mpg.de/ The Department „Regulation in Infection Biology“ headed by Max Planck Director Prof. Emmanuelle Charpentier is seeking a Technical Assistant (m/f) (RNA-seq experience) for a full-time employment (39 hours/week) of initially 2 years. Responsibilities: ...
Read More »Scientists develop RNA-Seq blood test for tuberculosis, the top infectious disease killer globally
from Bioscience Technology by Bevin Fletcher – An international team of scientists have developed a blood test, based on biomarkers in gene activity that can reliably predict whether a person with the Mycobacterium tuberculosis bacterium will develop active tuberculosis (TB). ...
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