Tag Archives: microrna

miRNA Temporal Analyzer (mirnaTA) – for identifying differentially expressed microRNAs in temporal studies using normal quantile transformation

rna-seq

Many open-source bioinformatics tools to identify existing and/or discover novel miRNAs in next-generation sequencing (NGS) reads have become available. While miRNA identification and discovery tools are significantly improved, the development of miRNA differential expression analysis tools, especially in temporal studies, ...

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Upcoming Webinar – Recent Work & Current Methods for Profiling Extracellular microRNAs

rna-seq

Date: Tuesday Sept 30, 2014 In the past, differential profiling and functional studies of microRNA (miRNA) has been performed mainly using tissues samples collected by invasive methods. However, in a clinical setting, more convenient and non-invasive methods are required, such ...

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Hypoxic signature of microRNAs in glioblastoma: insights from small RNA deep sequencing

rna-seq

Hypoxia is a critical aspect of the glioma microenvironment and has been associated with poor prognosis and resistance to various therapies. However, the mechanisms responsible for hypoxic survival of glioma cells remain unclear. Recent studies strongly suggest that microRNAs act ...

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miRSeq – A User-Friendly Standalone Toolkit for Sequencing Quality Evaluation and miRNA Profiling

rna-seq

MicroRNAs (miRNAs) present diverse regulatory functions in a wide range of biological activities. Studies on miRNA functions generally depend on determining miRNA expression profiles between libraries by using a next-generation sequencing (NGS) platform. Currently, several online web services are developed ...

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An efficient and sensitive method for preparing cDNA libraries from scarce biological samples

rna-seq

The preparation and high-throughput sequencing of cDNA libraries from samples of small RNA is a powerful tool to quantify known small RNAs (such as microRNAs) and to discover novel RNA species. Interest in identifying the small RNA repertoire present in ...

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Upcoming microRNA Focused Meeting

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miRNA World 2014 will provide the industry’s definitive platform maximizing the clinical potential of miRNAs. By bringing together the academic, pharmaceutical and biotechnology leaders who are leading this dynamic area of research, miRNA World 2014 will be discussing the biggest ...

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Web Tools for miRNA Analysis

rna-seq

An overview of databases and repositories of miRNA sequences and expression, a commentary on miRNA target prediction algorithms, tools for miRNA functional investigation, and online pipelines for the analysis of high throughput experiments. Examples and case studies are provided at ...

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