Tag Archives: non-coding rna

Chemist seeks new understanding of RNA

rna-seq

By Kenny Berkowitz –  As an undergraduate at Latvia’s Riga Technical University, Eriks Rozners found himself drawn to RNA, challenged by the complexity of its molecular structure, which is more flexible and less stable than that of DNA. Nearly 30 ...

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RNAcentral 1.0 provides a single access point to non-coding RNA data, vastly improving research into gene products

rna-seq

RNAcentral, the first unified resource for all types of non-coding RNA data, has been launched today by the RNAcentral Consortium. It aggregates information from a federation of expert databases, and provides tools for easy browsing. The initial release of RNAcentral ...

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RNA-Seq of the Nucleolus Reveals Abundant SNORD44-Derived Small RNAs

rna-seq

Small non-coding RNAs represent RNA species that are not translated to proteins, but which have diverse and broad functional activities in physiological and pathophysiological states. The knowledge of these small RNAs is rapidly expanding in part through the use of ...

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MIRPIPE – quantification of microRNAs in niche model organisms

rna-seq

MicroRNAs represent an important class of small non-coding RNAs regulating gene expression in eukaryotes. Present algorithms typically rely on genomic data to identify miRNAs and require extensive installation procedures. Niche model organisms lacking genomic sequences cannot be analyzed by such ...

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Transcriptome sequencing uncovers altered long intergenic non-coding RNAs

Long intergenic non-coding RNAs (lncRNAs) represent an emerging and under-studied class of transcripts that play a significant role in human cancers. Due to the tissue- and cancer-specific expression patterns observed for many lncRNAs it is believed that they could serve ...

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Visualization of nucleotide substitutions in the (micro)transcriptome

rna-seq

RNA-related applications of the next-generation sequencing (NGS) technologies require context-specific interpretations: e.g., sequence mismatches may indicate sites of RNA editing, or uneven read coverage often points to mature form of microRNA. Existing visualization tools traditionally show RNA molecules in two ...

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