Tag Archives: Proteomics informed by transcriptomics

RNA sequencing is a powerful method to build reference transcriptome assemblies and eventually sample-specific protein databases for mass spectrometry-based analyses. This novel proteomics informed by transcriptomics (PIT) workflow improves sample-specific proteome characterization of dynamic- and especially non-model organism proteomes, and ...

Mass spectrometry-based methods allow for the direct, comprehensive analysis of expressed proteins and their quantification among different conditions. However, in general identification of proteins by assigning experimental mass spectra to peptide sequences of proteins relies on matching mass spectra to ...