PCR-based RNA splicing assays are commonly used in diagnostic and research settings to assess the potential effects of variants of uncertain clinical significance in BRCA1 and BRCA2. The Evidence-based...
Read More »Comparison of Approaches for Multi-Level RNA-Seq Data
RNA sequencing (RNA-seq) is widely used for RNA quantification across environmental, biological and medical sciences; it enables the description of genome-wide patterns of expression and the deduction of regulatory interactions and networks. The aim of computational analyses is to achieve ...
Read More »Quantitative approaches for investigating the spatial context of gene expression
The spatial information associated with gene expression is important for elucidating the context-dependent transcriptional regulation during development. Recently, high-resolution sampling approaches, such as RNA tomography or single-cell RNA-seq combined with fluorescence in situ hybridization (FISH), have provided indirect ways to ...
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