Researchers at Oregon State University have used deep learning to decipher which ribonucleic acids have the potential to encode proteins. The gated recurrent neural network developed in the College...
Read More »ARC-seq – Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations
Transcriptional mutagenesis (TM) due to misincorporation during RNA transcription can result in mutant RNAs, or epimutations, that generate proteins with altered properties. TM has long been hypothesized to play a role in aging, cancer, and viral and bacterial evolution. However, ...
Read More »New Paper Demonstrates Novel Method for Detecting miRNA to Improve Liver Toxicity Testing
Single molecule microRNA technology proves useful for liver toxicity detection Breakthrough research published in PLOS ONE demonstrates quantitative, PCR-free detection of microRNA https://www.eurekalert.org/pub_releases/2017-07/q-smm062917.php Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, ...
Read More »SePIA – RNA and small RNA sequence processing, integration, and analysis
Large-scale sequencing experiments are complex and require a wide spectrum of computational tools to extract and interpret relevant biological information. This is especially true in projects where individual processing and integrated analysis of both small RNA and complementary RNA data ...
Read More »TGen pioneers RNA sequencing for patient care
from AZ Business Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the ...
Read More »Reducing error rates in third-generation sequencing technology
Nanopore DNA sequencing via transverse current has emerged as a promising candidate for third-generation sequencing technology. It produces long read lengths which could alleviate problems with assembly errors inherent in current technologies. However, the high error rates of nanopore sequencing ...
Read More »Chemist seeks new understanding of RNA
By Kenny Berkowitz – As an undergraduate at Latvia’s Riga Technical University, Eriks Rozners found himself drawn to RNA, challenged by the complexity of its molecular structure, which is more flexible and less stable than that of DNA. Nearly 30 ...
Read More »Featured RNA-Seq Job – Research Technician – Epigenomics Facility
Position – Research Technician C Institution – Yeshiva University (Eisenstein, WI) Description Epigenomics Facility is searching for a Research Technician C to work with DNA and RNA for Resequencing, ChIP-seq, RNA-seq, small RNA-seq and HELP-tagging and bisulfite sequencing assays on ...
Read More »XSAnno – a framework for building ortholog models in cross-species transcriptome comparisons
The accurate characterization of RNA transcripts and expression levels across species is critical for understanding transcriptome evolution. As available RNA-seq data accumulate rapidly, there is a great demand for tools that build gene annotations for cross-species RNA-seq analysis. However, prevailing ...
Read More »RNA World 2.0
from The Scientist Most scientists believe that ribonucleic acid played a key role in the origin of life on Earth, but the versatile molecule isn’t the whole story. The ubiquity and diverse functionality of ribonucleic acid (RNA) in today’s world ...
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