Most existing dimensionality reduction and clustering packages for single-cell RNA-Seq (scRNA-Seq) data deal with dropouts by heavy modelling and computational machinery. Here researchers from the Victor Chang Cardiac Research Institute introduce CIDR (Clustering through Imputation and Dimensionality Reduction), an ultrafast ...
Read More »SPADE – visualization and cellular hierarchy inference of single-cell data
High-throughput single-cell technologies provide an unprecedented view into cellular heterogeneity, yet they pose new challenges in data analysis and interpretation. In this protocol, researchers from Stanford University describe the use of Spanning-tree Progression Analysis of Density-normalized Events (SPADE), a density-based ...
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