Tag Archives: Single-cell

Obtaining data from single-cell transcriptomic sequencing allows for the investigation of cell-specific gene expression patterns, which could not be addressed a few years ago. With the advancement of droplet-based protocols the number of studied...

Single-cell omics provide insight into cellular heterogeneity and function. Recent technological advances have accelerated single-cell analyses, but workflows remain expensive and complex. Researchers at Roche Sequencing Solutions present a method enabling simultaneous, ultra-high throughput single-cell barcoding of millions of cells ...

How to Analyze Single Cell RNA-Seq Data: Point, Click, Done June 24, 2020 11:00 a.m. EDT ************** *REGISTER* ************** Single cell mRNA sequencing allows for the identification of different cell subtypes in a progenitor population. During pancreatic development, Neurog3 positive ...

The ability to interrogate total RNA content of single cells would enable better mapping of the transcriptional logic behind emerging cell types and states. However, current RNA-seq methods are...

Despite longstanding appreciation of gene expression heterogeneity in isogenic bacterial populations, affordable and scalable technologies for studying single bacterial cells have been limited. Although single-cell RNA sequencing (scRNA-seq) has...

Many severe symptoms in Parkinson’s disease are caused by the degeneration of the brain’s dopamine neurons. Transplantation of stem cell-derived dopamine neurons to patients with Parkinson’s disease is a therapeutic approach that is getting close to...

Researchers from Stefan Kubicek's and Christoph Bock’s groups, at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, have developed a method to...

BioTuring has recently launched their Big Data Portal. This enables scientists worldwide to connect to their server and analyze in real time the largest collections of single-cell datasets. With a lot of engineering effort (100X in speed improvement of gene ...

The scale and capabilities of single-cell RNA-sequencing methods have expanded rapidly in recent years, enabling major discoveries and large-scale cell mapping efforts. However, these methods have not been systematically and comprehensively...

Tissue transcriptomics is a family of techniques designed to allow transcriptomic profiling of cells within a tissue. It has gained a lot of attention over the past two years and is paralleling and extending advances made in single cell RNA-Seq ...