Opossum – pre-processing sequencing data for reliable SNP variant detection

February 28, 2017 Leave a comment 6,290 Views

Identifying variants from RNA-seq (transcriptome sequencing) data is a cost-effective and versatile alternative to whole-genome sequencing. However, current variant callers do not generally behave well with RNA-seq data due to reads encompassing intronic regions. Researchers from the Wellcome Trust Centre ...

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