Tag Archives: subSeq

Reduction of Gene Expression Variability from Single Cells to Populations follows Simple Statistical Laws

rna-seq

Recent studies on single cells and population transcriptomics have revealed striking differences in global gene expression distributions. Single cells display highly variable expressions between cells, while cell populations present deterministic global patterns. The mechanisms governing the reduction of transcriptome-wide variability ...

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subSeq – Determining appropriate sequencing depth through efficient read subsampling

rna-seq

Next-generation sequencing experiments, such as RNA-Seq, play an increasingly important role in biological research. One complication is that the power and accuracy of such experiments depends substantially on the number of reads sequenced, so it is important and challenging to ...

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