Omics-profiling is a collection of increasingly prominent approaches that result in large-scale biological datasets, for instance capturing an organism’s behavior and response in an...
Read More »Self-assembling manifolds in single-cell RNA sequencing data
Single-cell RNA sequencing has spurred the development of computational methods that enable researchers to classify cell types, delineate developmental trajectories, and measure...
Read More »Transcriptional benchmarking of in vitro cells to in vivo with single-cell rna-seq
Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of these subsets at scale require faithful in vitro models of ...
Read More »Open position for a biostatistician / computational biologist
The Centre for Research in Agricultural Genomics (CRAG) is currently seeking a biostatistician / computational biologist to join its Bioinformatics Core Unit, in the Molecular Data Analysis area. The main focus of the area is to perform and help the ...
Read More »RNA-Seq reveals a novel therapeutic strategy for ALS treatment
Amyotrophic lateral sclerosis (ALS) is a fatal heterogeneous neurodegenerative disease that lacks effective treatment option. Researchers at Genervon Biopharmaceuticals hypothesized that the traditional single-target approach to treat neurodegenerative...
Read More »Featured RNA-Seq Job – Computational and Systems Biology
Scientist II, Computational and Systems Biology Date: Oct 16, 2017 Location: Cambridge, MA, US Company: Biogen External Posting Title Scientist II, Computational and Systems Biology Job Description We are seeking a talented computational biologist that has experience in applying systems ...
Read More »Post-doc position available – single cell RNA-Seq
A Postdoctoral position is available in the laboratory of Peter Sims at Columbia University Medical Center in the Dept. of Systems Biology. The Sims Lab develops and applies new tools for genome- and transcriptome-wide analysis of individual cells using cutting-edge ...
Read More »UCLA Researchers introduce “RADIOTRANSCRIPTOMICS”- A synergy of imaging and transcriptomics in clinical assessment
Recent advances in quantitative imaging and “omics” technology have generated a wealth of mineable biological “big data”. With the push towards a P4 “predictive, preventive, personalized, and participatory” approach to medicine, researchers began integrating complementary tools to further tune existing ...
Read More »Proteome profiling outperforms transcriptome profiling for co-expression based gene function prediction
Co-expression of mRNAs under multiple conditions is commonly used to infer co-functionality of their gene products despite well-known limitations of this “guilt-by-association” (GBA) approach. Recent advancements in mass spectrometry-based proteomic technologies have enabled global expression profiling at the protein level; ...
Read More »Featured RNA-Seq Job – Senior Bioinformatician
SENIOR BIOINFORMATICIAN / 40 HOURS / DAY / BWH – GENETICS – (3022854) GENERAL SUMMARY/ OVERVIEW STATEMENT: This position will work with the NIH funded Accelerating Medicines Partnership, which brings high-level government, industry and non-profit foundation partners together to identify and validate ...
Read More »