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Tag Archives: University of California – Riverside

RNA sequencing reveals gene expression changes after oil exposure in Gulf of Mexico fish

July 14, 2016 Leave a comment 2,194 Views

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RIVERSIDE, Calif. – The Deepwater Horizon (DWH) oil spill, in which nearly three million barrels of crude oil got released in 2010 into the northern Gulf of Mexico, is the worst oil disaster in US history, contaminating the spawning habitats ...

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Cardioprotection of Panax Notoginseng saponins against acute myocardial infarction and heart failure through inducing autophagy.
METTL3 restrains papillary thyroid cancer progression via m6A/c-Rel/IL-8 mediated neutrophils infiltration.
Identify immune-related genes of adzuki bean weevil (Callosobruchus chinensis) in response to bacteria challenge by transcriptome analysis.
Galectin-1-RNA interaction map reveals potential regulatory roles in angiogenesis.
Coconut genome assembly enables evolutionary analysis of palms and highlights signaling pathways involved in salt tolerance.
RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization.

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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    Single-cell Multi-Omics: Marrying RNA Seq to protein expression and more

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