Detailed knowledge about the dynamics of SARS-CoV-2 infection is important for uncovering the viral and host factors that contribute to COVID-19 pathogenesis. Old-World nonhuman primates recapitulate mild to moderate cases of COVID-19, thereby...
Read More »Researchers use single cell RNA sequencing to identify cells likely targeted by Covid-19 virus
Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection. Researchers at MIT; the Ragon...
Read More »Theragen Etex develops sensitive RNA sequencing system to analyze COVID-19 RNA
Unlike the existing diagnostic kits that detect three genes from the Covid-19 virus, Theragen Etex’s newly developed system can reveal 30,000 ribonucleic acid sequences of Covid-19, the company said. SARS-CoV-2, the virus responsible...
Read More »Uniform analysis of coronavirus and SARS-COV-2 nanopore direct RNA sequencing datasets
Researchers from the Centre for Genomic Regulation (CRG) have launched a new database to advance the international research efforts studying COVID-19. The publicly-available, free-to-use resource (https://covid.crg.eu) can be used by researchers from around the world to study how different variations of the ...
Read More »VirusDetect – a new pipeline for virus identification
Researchers studying the viruses that affect agricultural production or human health now have a new tool for investigating where viruses have spread, on a local, national, or even global scale. VirusDetect is a free, open-source bioinformatics pipeline that can efficiently ...
Read More »Researchers employ RNA-Seq to monitor the diversity of viruses affecting animal health
The porcine reproductive and respiratory syndrome (PRRS) virus mutates rapidly, especially European strains, creating a challenge for diagnostic laboratories to monitor the disease. Today, Thermo Fisher Scientific presented research at the Pig Veterinary Society (IPVS) Congress showing the genetic diversity ...
Read More »Researchers and public health officials use RNA-Seq to track transmission of epidemic viruses
(IEEE Spectrum) -Using a genome sequencer smaller than a stapler, geneticists have demonstrated the role they can play in combating outbreaks of infectious disease. An eight-month experiment in Guinea during the tail end of the Ebola outbreak, described today in ...
Read More »RNA-Seq reveals why mosquitoes don’t suffer from the infections they pass on
Researchers from CSIRO Health and Biosecurity have published findings that start to explain how mosquitoes respond to viral infections. Using an RNA-sequencing approach, they identified a number of genes from multiple cellular pathways that play integral roles in protecting mosquitoes from ...
Read More »MIRALCS – microwell full-length mRNA amplification and library construction from a single-cell
Viral infection causes multiple forms of human cancer, and HPV infection is the primary factor in cervical carcinomas. Recent single-cell RNA-seq studies highlight the tumor heterogeneity present in most cancers, but virally induced tumors have not been studied. HeLa is ...
Read More »HeLa RNA is everywhere
from the Virology Blog By Vincent Racaniello The first immortal human cell line ever produced, HeLa, originated from a cervical adenocarcinoma taken from Henrietta Lacks. The cell line grew so well that it was used in many laboratories and soon ...
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